The Centers for Disease Control and Prevention’s (CDC) 6|18 Initiative: Accelerating Evidence into Action promotes the adoption of evidence-based interventions that can improve health and control costs related to six high-burden, high-cost health conditions — tobacco use, high blood pressure, inappropriate antibiotic use, asthma, unintended pregnancies, and type 2 diabetes.

This Center for Health Care Strategies (CHCS) resource center, made possible through support from the Robert Wood Johnson Foundation, is designed to advance implementation of CDC’s 6|18 Initiative by Medicaid, state and local health departments, and other payers and purchasers. It offers practical resources and state examples to guide stakeholders in spending smarter for healthier populations.


  • Improve health and control costs using specific evidence-based interventions
  • Develop sustainable collaboration between public health and health care sectors


How Can You Get Started?

Explore the topics below to learn how to apply CDC’s 6|18 evidence-based strategies to improve population health:

What is CDC’s 6|18 Initiative?

Background and frequently asked questions about CDC’s 6|18 Initiative.

CDC’s 6|18 Initiative in Action

Summary of state prevention-focused 6|18 Initiative activities, including profiles on select states.

General Implementation Tools

General resources to help stakeholders design and implement CDC’s 6|18 Initiative strategies.


Priority Condition Implementation Resources

Access an array of condition-specific resources to guide the implementation of CDC’s 6|18 evidence-based interventions: