The Centers for Disease Control and Prevention’s (CDC) 6|18 Initiative: Accelerating Evidence into Action promotes the adoption of evidence-based interventions that can improve health and control costs related to six high-burden, high-cost health conditions — tobacco use, high blood pressure, inappropriate antibiotic use, asthma, unintended pregnancies, and type 2 diabetes.

This Center for Health Care Strategies (CHCS) resource center, made possible through support from the Robert Wood Johnson Foundation, is designed to advance implementation of CDC’s 6|18 Initiative by Medicaid, state and local health departments, and other payers and purchasers. It offers practical resources and state examples to guide stakeholders in spending smarter for healthier populations. Learn about state technical assistance activities for CDC’s 6|18 Initiative


  • Improve health and control costs using specific evidence-based interventions
  • Develop sustainable collaboration between public health and health care sectors


How Can You Get Started?

Explore the topics below to learn how to apply CDC’s 6|18 evidence-based strategies to improve population health:

What is CDC’s 6|18 Initiative?

Background and frequently asked questions about CDC’s 6|18 Initiative.

CDC’s 6|18 Initiative in Action

Summary of state prevention-focused 6|18 Initiative activities, including profiles on select states.

General Implementation Tools

General resources to help stakeholders design and implement CDC’s 6|18 Initiative strategies.


Priority Condition Implementation Resources

Access an array of condition-specific resources to guide the implementation of CDC’s 6|18 evidence-based interventions: